In the past few days, the serious invasion of Streptococcus suis in a number of villages in Ziyang, Sichuan province has aroused great concern in the community. Yesterday, the reporter interviewed Xu Jianguo, director of the Center for Infectious Disease Prevention and Control at the CDC (China Center for Disease Control and Prevention). Most of the patients were slaughtered, trafficked, and cooked. Occupational skin damage was the most likely to cause infection. According to the results of epidemiological investigation of the epidemic by the CDC of Sichuan Province, the municipality and the county, published by the China CDC on July 25, Of the 55 cases of rural swine streptococcal infection in rural areas, 49 cases had a clear history of exposure, of which 47 cases were contacted with dead pigs and 2 were contacted with dead animals. The exposure methods included direct contact with dead pigs (sheep) such as feeding, slaughter, sale, washing, cutting, eating, burial, etc., and 37.2% of the cases had contact with damaged or scratched arm skin. Xu Jianguo told reporters that the infection of humans with Streptococcus suis is a rare condition. Most cases of this kind have been reported internationally, with slaughter, trafficking, and cooking as occupations. Although there have been reports of cases of eating pigs that had been dying, the possibility of digestive tract infections cannot be ruled out. However, the most common form of infection reported has been the contact of pork with Streptococcus suis on wounded skin. Xu Jianguo said that as a Gram-positive coccus, streptococci can be divided into 20 serogroups according to serological reactions. Among them, R and F groups can cause pig disease and can also cause human morbidity. In recent years, there have been reports from abroad of several cases of Streptococcus suis type 2 infection in the R group. However, the number of reported cases per patient is small, and it is usually 1-2 cases. Healthy pigs also carry streptococcal bacteria but not necessarily pathogenicity In order to strengthen the response to "bursty" abilities, the Chinese CDC has increased a large number of projects for rare infectious diseases in recent years. Since last year, research on swine streptococci has been included in the scope of research of the Institute for the Prevention and Control of Infectious Diseases. A Ph.D. student led by Xu Jianguo launched the Streptococcus suis technical reserve and research project in 2004. It has been for one year. Related data collection and research. The epidemic broke out. The researcher entered the laboratory on the early morning of July 19th. On the 20th, he obtained Streptococcus suis from the dead pigs. On the 21st, Streptococcus suis was obtained from the specimen of the dead and was completed on the 22nd. The analysis and identification of the strains obtained from patients and sick animals completed the virulence gene sequencing analysis of the strains obtained from patients and diseased animals on the 25th. According to reports, epidemiological data show that Streptococcus suis type 2 can cause pig disease, high mortality, no obvious seasonal incidence, occur throughout the year. Epidemiological data also indicate that healthy pigs also carry Streptococcus suis type 2, but Streptococcus suis type 2 may not necessarily be pathogenic. A survey conducted by the Jiangsu Veterinary Research Institute in China showed that the prevalence of Streptococcus suis type 2 in normal herds was high, averaging 42.6%. Studies in Australia and New Zealand showed that 75% of healthy pigs carried S. suis, and 3% of healthy pigs had positive blood cultures, but no disease. Xu Jianguo said that whether Streptococcus suis type 2 has pathogenicity depends on the size of its virulence. The virulence may be related to many virulence factors such as capsular polysaccharides. However, what exactly affects the virulence of the bacteria is still a mystery. Only one generation of patients had not yet found a case of human transmission from the scene of the epidemic in Sichuan. On the morning of July 4th, a surnamed Wang peasant helped neighbors slaughter the dead pigs. He had a fever that night and was admitted to the hospital the next morning at 12 o'clock noon. Left and right died, and the neighbors he helped, although there were successive sick and dead pigs in the family, none of them had become ill. Among the dozens of patients, none of the family members became ill due to the care of the patient. Xu Jianguo pointed out that human and livestock diseases caused by Streptococcus suis type 2 is an important zoonosis. Although it is an infectious disease, there is no evidence that the disease has spread from person to person, nor has it been discovered with other obvious Common exposures such as animals, food and water. Regardless of the epidemic in Sichuan, or the previous reported epidemic, only one case has occurred. Xu Jianguo said that the large number of domestic animals needed to be monitored for disease prevention. Excessive breeding density, hygienic conditions, long-distance transportation, climate change and other stress factors may affect the health status of livestock. Although the current research cannot answer the specific cause of the occurrence and prevalence of swine streptococcus disease, it is undoubtedly a prerequisite for the protection of human health. What is certain is that as long as the Streptococcus suis is prevented from occurring in domestic animals, this epidemic will not infringe upon humans. 117 Cases of Streptococcus suis Infected with Streptococcus suis in Guangdong According to the Ministry of Health website, according to the report of the Sichuan Provincial Health Department, as of 12:00 on July 26th, there were 117 cases of swine streptococcal disease in Sichuan cumulative reports, including laboratory confirmation. In 5 cases, 71 were clinically diagnosed and 41 were suspected. Of these cases, 5 were cured and discharged, 21 were critically ill, and 24 died. On July 26, the relevant departments of Sichuan Province held a press conference to inform the media of the latest situation of swine streptococci in Ziyang: the number of dead pigs in Ziyang City in the past 6 days did not show an upward trend. The immunization vaccine was already in Guangdong. A biological treatment plant emergency production. Chen Huanchun, an expert from the Ministry of Agriculture and an academician of the Chinese Academy of Engineering, told reporters that the outbreak was caused by Streptococcus suis type 2 infection. Experts of the Ministry of Agriculture have extracted the strain of streptococcus that caused the outbreak and the immunization vaccine has been used in a biological treatment plant in Guangdong. Emergency production can be completed in a week or so and it can be used to prevent immunity after passing the test. According to reports, Streptococcus suis disease is a class II animal epidemic that is regulated by the State. It is a zoonotic infectious streptococcus pyogenes that is widely distributed and is often found in healthy mammals and humans. Induction of animal body resistance and changes in the external environment, will cause animal and human hair glass some common drugs, such as: cephalosporins, penicillin, cephalosporin, levofloxacin, etc. can control. At present, the cases occurring in the Sichuan region are scattered and there is no obvious epidemiological connection between them; there is no evidence that the disease is transmitted from person to person. The possibility of infection through mosquito bites is very similar. Streptococcus suis disease is generally transmitted to humans through wounds, digestive tracts, etc. As long as private pigs are killed and diseased pigs are not eaten, there will be no infection. Qukuning, director of Sichuan Animal Husbandry and Food Bureau, told reporters that after the occurrence of swine streptococcus disease in Ziyang City and Zizhong County, Neijiang City, due to the timely and effective treatment and prevention and control measures, the products were processed and processed by designated slaughter and processing companies in Sichuan Province. The pork is strictly quarantine tested, is safe, you can rest assured that eating.
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