New research shows that brain circuits can be repaired to help cure Parkinson's disease

Recently, according to foreign media reports, a new study by Jeffrey Marcus and its research team at the Stem Cell Research Institute at Harvard University in the US showed that neuronal transplantation can repair damaged brain circuits. This finding is expected to promote the treatment of brain-damaged diseases such as autism and Parkinsonism.

It is reported that these scientists took out neurons from healthy mouse embryos and transplanted them into adult obese mice with missing obese hormones (ie, leptin). The function of obesity hormones is to promote metabolism, suppress appetite, and control body weight.

The study found that these neurons survived in adult rats, incorporated into their brain circuits, and were differentiated into four neurons, which integrate with existing neurons and respond to obesity hormones, insulin, and glucose. The above shows that implanted neurons have repaired the brain circuits of adult rats. Rats that received neuron transplants were 30% lighter than their untreated counterparts.

For the results of this study, scientists said that their research goal is to treat Parkinson's disease, autism, epilepsy and other motor neuron diseases and spinal injury, the study of obesity symptoms because its visual effects are more obvious.

Markis said: "We use complex (brain) circuits to do experiments to see if the transplanted neurons can be reconnected by carefully selected and controlled neurons. Studies have shown that neurons can not only evolve into corresponding The cells can also send and receive signals from the recipient's brain."

In view of the success of this experiment, Maxlis is full of confidence in future research. He said: "We will next study whether transplanted neurons can repair other brain circuits and spinal cord nerves. These will involve motor neuron diseases and spinal cord injury. As for whether we can reshape the brain circuits of mammals, I think we is allowed."