Hemorrhagic disease of grass carp is a kind of infectious disease that causes grass carp to be more harmful at the stage of fish species. It is widely endemic, and the incidence and mortality are high. The disease can be divided into three types. The first is "red muscle type". The diseased fish is dark and reddish, with no obvious bleeding on the outside, or with slight bleeding, with marked muscle congestion, and often the body's muscles are red. Diseased fish less than 10 cm, with sunlight or light perspective, visible subcutaneous congestion; sick fish more than 10 cm, after stripping the skin, the muscles were a little or plaque-like congestion. In severe cases, the body's muscles are hyperemia and appear bright red. There are no obvious symptoms in the ankle, and a few severe cases have the phenomenon of "whiteness". This type of smaller grass carp is more common. The second is the "red fin red cover type." The diseased fish had obvious bleeding in the mouth, jaw, lid, around the eyelids and at the base of each fin, and some had bleeding under the scales. Muscles were a bit like bleeding or systemic bleeding, most of the intestinal tract congestion, a small number of diseased fish intestine and muscle bleeding was not obvious. This type mostly appears in larger grass carp. The third is "enteritis type". Mainly in the intestinal part of the diseased fish or the whole intestine was bright red due to bleeding, especially the micro-vessel congestion in the intestinal wall, body surface and muscle bleeding phenomenon is not obvious, a small number of diseased fish liver, spleen, kidney and other organs local bleeding Or pale due to blood loss. This type is found in both large and small grass fingerlings. The occurrence of bleeding disorders is related to the stocking density of fingerlings. In general, the incidence of denser ponds is higher than that of the dilute pools. More than 8 points of grass carp species may have this disease. During its popular season, generally from late June to the end of October, the water temperature below 25 °C, the condition gradually disappeared. According to the speed of development of the disease, the disease can be divided into acute type and chronic type. Acute type. The onset was acute, the manacing was fierce, and the death was severe. He died a great deal within 3-5 days after the onset of the disease. Death peaks occurred around 10 days, and most died after 2-3 weeks. Mainly in the high density of grass carp single pool. Chronic type. The condition began to ease, with several deaths per day to more than 10 deaths. The peak of death was not obvious, but the duration of the disease was long and it was not until the end of October that the dead fish were stopped. The chronic type mostly occurs in large-sized fingerlings ponds that are diluted in mid-August. Prevention methods. Prevention and treatment of grass carp hemorrhagic disease should be based on prevention. Artificial injecting formalin-inactivated vaccine or immunostimulating immunohistochemistry should be adopted to enable the fish to produce immunity and to safely survive the bleeding season of the year. In the treatment of bleeding disorders, the combination of external (sprinkling) and internal medicines works well. Topical drugs. The whole pool can be sprinkled with copper sulphate or copper chloride, so that the pool water concentration is 0.70 mg/kg. However, copper sulfate should be applied twice (once every other day). Also can be used throughout the pool sprinkled with enemy spirit, pool water is 0.60 mg / kg concentration. Internal medication. (1) To feed three yellow baits, that is, 100-150 grams of each 10,000 fish species, rhubarb, berberine, and scutellaria baicalensis, and pulverize the crushed fish into boiling water or hot boiled water overnight, and feed the mixed bait for 2-3 consecutive days. (2) 200 pieces of rhubarb soda per hundred pounds of fish, 10 pieces of sulfadiazine, and minced bait fed fish for 4-5 consecutive days. (3) Each 10,000 species of fish (or 50 kg of fingerlings) should be fed with 4 kg of peanuts, 0.25 kg of garlic, and 0.25 kg of salt. Two times a day, even for 4 days.
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